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InSitu Biologics

Updates

December 04
Over $2M in Investments Using Reg A+ Mini-IPO to Advance Non-Opioid Pain Drug Candidate into Clinical Trials

WOODBURY, Minn., Dec. 4, 2018 /Press Release/ -- InSitu Biologics, Inc., an emerging biotech company focusing on the development of AnestaGel™, has received over $2 million in investments. InSitu is believed to be in the midst of the largest Reg A+ round for a pre-revenue biotech company and anticipates investments reaching $10 million in 2019.

 

Since its Reg A+ launch, InSitu Biologics has sold-out of three SEC qualified price tiers. InSitu has since paused its Offering and will be submitting a new valuation and price qualification to the SEC to better reflect milestone achievements and business developments.

 

In pre-clinical studies, AnestaGel has proven to be a fast acting and long lasting, non-opiate painkiller, targeted for use in post-operative regional pain management and is expected to be explored for use in numerous surgical applications. Prior to the Reg A+ funding, InSitu Biologics published a peer-reviewed preclinical study in the Journal of Pain Research which found that AnestaGel:

  • Consistently lasted up to 300% longer when compared to the leading liposome-based sustained-release drug;
  • Had full nerve block beyond 72 hours (24-48 hours for liposome-based drug) and;
  • Carried 8x more painkiller than liposome-based drugs, remaining non-toxic.

"Development of non-addictive, non-opioid pain drugs lag far behind research for other diseases," said James Segermark, President and CEO. "Addiction often begins with post-operative pain management, for which there are few non-opiate solutions. Our investors understand that a change is required."

 

The Securities and Exchange Commission (SEC) Qualified InSitu on July 17, 2018, to raise up to $10 million using Reg A+. Reg A+ allows private companies to raise up to $50 million from the general public over a 12 month period. The SEC qualified Form 1-A can be found here: https://www.sec.gov/Archives/edgar/data/1723443/000147793218002887/insitu_1a.htm

 

The Company is audited by the CPA firm of Baker Tilly Virchow Krause. The Offering Circular, and ability to make an investment reservation can be found at https://www.manhattanstreetcapital.com/insitu-biologics-0

 

Forward-Looking Statements

We caution that, whether or not expressly stated, certain statements made in this news release that reflect management's expectations regarding future events and economic performance are forward-looking in nature and, accordingly, subject to risks and uncertainties. All statements other than statements of historical facts included in this release are forward-looking statements. In some cases, forward-looking statements can be identified by words such as "believe," "expect," "anticipate," "plan," "potential," "continue" or similar expressions. Such forward-looking statements include risks and uncertainties, and there are important factors that could cause actual results to differ materially from those expressed or implied by such forward-looking statements. Investors should not place any undue reliance on forward-looking statements since they involve known and unknown, uncertainties and other factors which, in some cases, are beyond the Company's control which could, likely materially affect actual results, levels of activity, performance or achievements.

 

 

November 25
Update #3: Share Price, Speaker Panel, and News Sightings...

Our Tier 3 of 30,000 shares is nearly full and we will pause our Stock Offering on Tuesday, November 27, 2018. At that time we plan on submitting a new price and valuation to the SEC for qualification. Upon approval of the updated Stock Offering, we anticipate our offering will again be available for purchase in January, 2019. During the pause we’ll be taking reservations for the new share price.

 

In case you’ve missed it, our pricing and investments since July 17th are as follows:

 

Tier 1: 100% Filled at $5.75 Share Price | 275,661 Shares

Tier 2: 100% Filled at $6.85 Share Price | 43,126 Shares

Tier 3: 81% Filled at $6.90 Share Price | 30,000 Shares Available; [Paused on Tuesday, Nov. 27th]

 

Dr. Daniel Sipple will be at the 2018 G20 World Brain Mapping Therapeutics Summit in Buenos Aires, presenting on November 26th. The Summit aims to contribute to President Obama’s BRAIN initiative and to expand action on the current and upcoming initiatives across the G20 nations. Dr. Sipple will be a representative on the Brain and Spine Trauma and Opioid Crisis panel.

 

More props to Dr. Sipple with his mention in the Northwestern Medicine Magazine. https://magazine.nm.org/2018/11/12/progress-notes-5/

 

Dr. Jake Hutchins was interviewed about the newly FDA cleared drug, Dsuvia. Dsuvia, an opioid-based painkiller, has been a controversial FDA clearance. We agree with Dr. Jake Hutchins that "Dsuvia fills a gap that we don't have anything else to fill with". The full story and interview: http://www.startribune.com/u-doctor-in-middle-of-opioid-conflict/500756911/

 

MedCityNews, a leading healthcare innovation news source, interviewed us for their "Founders Story": https://medcitynews.com/2018/11/founders-story-insitu-biologics/

 

We will continue to report to you on a regular basis, however, please do not hesitate to drop me a line with any questions or comments. We remain focused on getting to Phase 1 with the best possible product. We expect our non-opiate, AnestaGel to be proven safe, fast acting, long lasting, injectable and smearable.

 

Regards,

James Segermark

President & CEO

InSitu Biologics, LLC

(651) 338-4801

October 19
Update #2: Tier 2 100% Filled, On to Tier 3 at $6.90

Quick update for shareholders and prospective investors.

 

We closed our Tier 2 $6.85 level with 43,126 shares sold. The SEC approved our Tier 3 with another share price increase to $6.90 which we have allotted 30,000 shares at this level. Over 10% has already been sold this week.

 

As a reminder we will be hosting Technology Updates in Orlando on October 26 & 27 at the Marriott Marquis from 5-8 on Friday & 9am-6pm on Saturday, and in Santa Barbara on Thursday, November 15, from 4-8pm at a site to be determined. Please join us or refer a friend.

 

If you haven't seen the latest podcast you can find that here: CEO Money interviews Jim Segermark

 

As always, thank you again for interest, and financial support.

 

Jim

 

Regards,

James Segermark

President & CEO

InSitu Biologics, LLC

(651) 338-4801

www.insitubiologics.com

September 14
Update #1: Meetups, Share Price, Podcasts...

This is Jim Segermark, CEO and Co-Founder of InSitu Biologics. Quick note to share our progress and upcoming events with you. If you live, or happen to be, in the St. Paul, Orlando or Santa Barbara area, please consider joining us at one of our Happy Hour Technology Updates, please see the details below.

 

What's New:

 

As many of you know we have been qualified by the SEC to raise up to $10 million from the sale of Common A Shares over the course of 12 months. Since July 31st, we’ve raised $1.8 million. Many thanks to all of you that have made an investment and taken the time to understand the opportunity AnestaGel™ presents.

 

We opened our IPO with an initial share price of $5.75 and quickly sold out. Since then, the SEC approved a share price increase of $6.85, of which we have about $100,000 remaining. We plan on going back to the SEC after that is sold, for a new price based on milestones achieved and actions we have taken.

 

We’ve been featured in two podcasts. You can find them here: CEO Money and Future Tech Podcast

 

A few of you have had questions regarding the investment process. There is now an FAQ format that may be helpful. Here is the link.

 

InSitu Biologics shares are now sold in all 50 states and throughout the world via our FINRA Broker Dealer, SageWorks Capital, LLC.

 

 

What's Coming Up:

 

Pre-Clinical GLP Study: We will begin what we believe is our final battery of tests for AnestaGel in multiple species. These begin on October 15.

 

FDA Pre-IND Meeting: We expect to meet with the FDA in the coming months to discuss the filing for our Phase 1 Clinical Study.

 

Introductions: We want your investor friends, family, colleagues, and other medical professionals to become shareholders and spread our message and investment opportunity. If you know someone that may be interested, feel free to drop me a note; I will personally follow up.

 

Let’s Get Together: We will be hosting Technology Updates in St. Paul on October 2, at Town & Country Club from 4-7pm, Orlando on October 26 & 27 at the Marriott Marquis from 5-8 on Friday & 9am-6pm on Saturday, and in Santa Barbara on Thursday, November 15, from 4-8pm at a site to be determined. Please join us and bring a friend.

 

Your questions and favorable comments are always welcome. If you have complaints, I will find someone for you to send those to… Thank you again for interest, and financial support

 

Regards,

James Segermark

President & CEO

InSitu Biologics, LLC

(651) 338-4801

www.insitubiologics.com

September 04
CEO Jim Segermark featured on Future Tech Podcast

CEO Jim Segermark was recently featured on the Future Tech Podcast where he talks about potential applications of the matrix biohydrogel and how AnestaGel™ works. 

Listen here: https://www.futuretechpodcast.com/podcasts/jim-segermark-insitubiologics-offering-non-opioid-long-lasting-biohydrogel-painkiller/

July 11
InSitu Biologics SEC Qualification Update

This is Jim Segermark, CEO of InSitu Biologics, Inc., with a quick update.

 

We continue to work with SEC to qualify our RegA+ Offering. You can now view the current version of the Offering Circular at www.insitubiologics.com or directly from the SEC website here.

 

When we are qualified to begin selling shares, you will get multiple emails, including one with specific instructions on how you can make your investment.  We will need approximately 24-36 hours after SEC qualification to begin receiving your investments.

 

Thank you for your patience.  We continue to make progress toward our Phase 1 Clinical Study, and I look forward to reporting on that to you in the future.

 

Regards,

James Segermark

President & CEO

InSitu Biologics, LLC

(651) 338-4801

www.insitubiologics.com

An offering statement regarding this offering has been filed with the SEC. The SEC has qualified that offering statement, which only means that the company may make sales of the securities described by the offering statement. It does not mean that the SEC has approved, passed upon the merits or passed upon the accuracy or completeness of the information in the offering statement. You may obtain a copy of the offering circular that is part of that offering statement from the here.
You should read the offering circular before making any investment.

The offering materials may contain forward-looking statements and information relating to, among other things, Insitu Biologics, its business plan and strategy, and its industry. These forward-looking statements are based on the beliefs of, assumptions made by, and information currently available to the company’s management. When used in the offering materials, the words “estimate,” “project,” “believe,” “anticipate,” “intend,” “expect” and similar expressions are intended to identify and constitute forward-looking statements. These statements reflect management’s current views with respect to future events and are subject to risks and uncertainties that could cause the company’s actual results to differ materially from those contained in the forward-looking statements. Investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date on which they are made. The company does not undertake any obligation to revise or update these forward-looking statements to reflect events or circumstances after such date or to reflect the occurrence of unanticipated events.

Securities are offered through Sageworks Capital, LLC., a registered broker-dealer and member FINRA/SIPC. Neither InSitu Biologics, Inc. nor Sageworks Capital, LLC provides any investment advice or make any investment recommendations to any persons, ever, and no communication through this website or in any other medium should be construed as such.  

InSitu Biologics, Inc. securities are not publicly traded and are intended for investors who do not need a liquid investment. This investment is NOT a bank deposit (and thus NOT insured by the FDIC or by any other federal governmental agency), are NOT guaranteed by Sageworks Capital, LLC or InSitu Biologics, Inc., and MAY lose value. Investors must be able to afford the loss of their entire investment. 
Any financial projections or returns shown on the website are illustrative examples only, and there can be no assurance that any valuations provided are accurate or in agreement with market or industry valuations. Investors should conduct their own due diligence, not rely on the financial assumptions or estimates displayed on this website, and are encouraged to consult with a financial advisor, attorney, accountant, and any other professional that can help you to understand and assess the risks associated with any investment opportunity. Please refer to the offering circular for full details and disclosures, including a subscription agreement should you choose to invest.

Insitu Biologics, Inc. is required to pay an advisory retainer fee of $6,000, plus the same value of warrants at the respective issue price. In addition, they will pay a technology admin and service fee of $25 per investor, plus the same value of warrants at the respective issue price. As of 11/30/2018 Insitu Biologics has paid $24,000 in fees.